Strain Data Sheet

RBRC11740

Strain Information

Image
BRC No.RBRC11740
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129-Dnah11<tm1(Venus)Hmd>
Former Common nameDnah11-Venus KI(F21)
H-2 Haplotype
ES Cell lineG4 [(129S6/SvEvTac x C57BL/6NCr)F1]
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components.
Takahiro Ide, Wang Kyaw Twan, Hao Lu, Yayoi Ikawa, Lin-Xenia Lim, Nicole Henninger, Hiromi Nishimura, Katsuyoshi Takaoka, Vijay Narasimhan, Xiumin Yan, Hidetaka Shiratori, Sudipto Roy, Hiroshi Hamada
PLoS Genet., 16(12):e1009232 (2020). 33347437

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Dnah11
MGI:1100864		dynein, axonemal, heavy chain 1112Dnah11<tm1(Venus)Hmd> targeted mutation 1, Hiroshi Hamada
  • primary ciliary dyskinesia 7(DisGeNET, MedGEN)
    • Venus Yellow Fluorescent Protein (Aequorea victoria)12Venus
    loxP phage P1 loxP12loxP

    Phenotype

    Phenotype annotation from literatures by Mammalian phenotype ontology
    Detailed phenotype data

    Ordering Information

    Donor DNAマウス Dnah11遺伝子, オワンクラゲ 改変型GFP遺伝子（Venus） (Gly4Ser)3 linker配列, 大腸菌 LoxP配列
    Research applicationCre/loxP system
    Fluorescent Proteins/lacZ System
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. 未発表In publishing the research results obtained by use of the BIOLOGICAL RESOURCE containing Venus, an acknowledgment to Dr. Atsushi Miyawaki and a citation of the following literature(s) designated by the DEPOSITOR are requested.
    Nat. Biotechnol., 20, 87-90 (2002).
    DepositorHiroshi Hamada (RIKEN BDR)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data