Strain Data Sheet

RBRC11744

Strain Information

Image
BRC No.RBRC11744
TypeCRISPR/Cas9Cartagena
SpeciesMus musculus
Strain nameB6-Bicc1<em1Hmd>
Former Common nameBicc1 delta exon1 #2
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Fluid flow-induced left-right asymmetric decay of Dand5 mRNA in the mouse embryo requires a Bicc1-Ccr4 RNA degradation complex.
Katsura Minegishi, Benjamin Rothé, Kaoru R Komatsu, Hiroki Ono, Yayoi Ikawa, Hiromi Nishimura, Takanobu A Katoh, Eriko Kajikawa, Xiaorei Sai, Emi Miyashita, Katsuyoshi Takaoka, Kana Bando, Hiroshi Kiyonari, Tadashi Yamamoto, Hirohide Saito, Daniel B Constam, Hiroshi Hamada
Nat. Commun., 12(1):4071 (2021). 34210974

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Bicc1
MGI:1933388
BicC family RNA binding protein 110Bicc1<em1Hmd> endonuclease-mediated mutation 1, Hiroshi Hamada
  • renal dysplasia, cystic, susceptibility to(MedGEN)
  • Phenotype

    Annotation by Mammalian phenotyhpe ontology
    Detailed phenotype data

    Ordering Information

    Donor DNAStreptococcus pyogenes tracrRNA, crRNA ,Cas9, Mouse a part of Bicc1 gene
    Research application
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Nat Commun. Jul 1;12(1):4071.(2021) doi: 10.1038/s41467-021-24295-2.
    DepositorHiroshi Hamada (RIKEN BDR)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data