Strain Data Sheet

RBRC11781

Strain Information

Image
BRC No.RBRC11781
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameSTOCK Wnt5b<tm1Hmd>
Former Common nameWnt5b KO
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Motor neurons with axial muscle projections specified by Wnt4/5 signaling.
Dritan Agalliu, Shinji Takada, Ilir Agalliu, Andrew P McMahon, Thomas M Jessell
Neuron, 61(5):708-20 (2009). 19285468

A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking.
Minegishi K, Hashimoto M, Ajima R, Takaoka K, Shinohara K, Ikawa Y, Nishimura H, McMahon A P, Willert K, Okada Y, Sasaki H, Shi D, Fujimori T, Ohtsuka T, Igarashi Y, Yamaguchi T P, Shimono A, Shiratori H, Hamada H
Dev. Cell., 40(5):439-452.e4(2017). 28292423

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Wnt5b
MGI:98959		wingless-type MMTV integration site family, member 5B6Wnt5b<tm1Hmd> targeted mutation 1, Hiroshi Hamada

Phenotype

Phenotype annotation from literatures by Mammalian phenotype ontology
Detailed phenotype data

Ordering Information

Donor DNAマウス Wnt5b遺伝子, マウス PGK1遺伝子のプロモーター, E.coli ネオマイシン耐性遺伝子, マウス PGK1遺伝子のpolyAシグナル配列
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Neuron, 61(5):708-20 (2009).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
DepositorHiroshi Hamada (RIKEN BDR)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data