Strain Data Sheet

RBRC11827

Strain Information

Image
BRC No.RBRC11827
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6-Derl1<tm1.1Nishi>
Former Common nameDerl1 f/f
H-2 Haplotype
ES Cell lineRENKA [C57BL/6NCrlCrlj]
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function.
Takashi Sugiyama, Naoya Murao, Hisae Kadowaki, Keizo Takao, Tsuyoshi Miyakawa, Yosuke Matsushita, Toyomasa Katagiri, Akira Futatsugi, Yohei Shinmyo, Hiroshi Kawasaki, Juro Sakai, Kazutaka Shiomi, Masamitsu Nakazato, Kohsuke Takeda, Katsuhiko Mikoshiba, Hidde L Ploegh, Hidenori Ichijo, Hideki Nishitoh
iScience, 24(7):102758 (2021). 34355142

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Derl1
MGI:1915069
Der1-like domain family, member 115Derl1<tm1.1Nishi>
MGI:6781627
targeted mutation 1.1, Hideki Nishitoh
Frt yeast FRT (flippase recombination target) site15Frt
loxP phage P1 loxP15loxP
loxP phage P1 loxP15loxP

Phenotype

Annotation by Mammalian phenotyhpe ontology
Detailed phenotype data

Ordering Information

Donor DNABacteriophage P1 loxP sites, yeast FRT (flippase recombination target) site, mouse Derl1 genomic DNA
Research applicationCre/loxP system
FLP/frt system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. iScience, 24(7):102758 (2021). doi: 10.1016/j.isci.2021.102758.
DepositorHideki Nishitoh (University of Miyazaki)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data