Strain Information | |
---|---|
Image | |
BRC No. | RBRC11827 |
Type | Targeted Mutation![]() |
Species | Mus musculus |
Strain name | B6-Derl1<tm1.1Nishi> |
Former Common name | Derl1 f/f |
H-2 Haplotype | |
ES Cell line | RENKA [C57BL/6NCrlCrlj] |
Background strain | |
Appearance | |
Strain development | |
Strain description | |
Colony maintenance | |
References | ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function. Takashi Sugiyama, Naoya Murao, Hisae Kadowaki, Keizo Takao, Tsuyoshi Miyakawa, Yosuke Matsushita, Toyomasa Katagiri, Akira Futatsugi, Yohei Shinmyo, Hiroshi Kawasaki, Juro Sakai, Kazutaka Shiomi, Masamitsu Nakazato, Kohsuke Takeda, Katsuhiko Mikoshiba, Hidde L Ploegh, Hidenori Ichijo, Hideki Nishitoh iScience, 24(7):102758 (2021). 34355142 |
Health Report | |
---|---|
Examination Date / Room / Rack |
Gene | |||||||
---|---|---|---|---|---|---|---|
Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Derl1 MGI:1915069 | Der1-like domain family, member 1 | 15 | Derl1<tm1.1Nishi> MGI:6781627 | targeted mutation 1.1, Hideki Nishitoh | |||
Frt | yeast FRT (flippase recombination target) site | 15 | Frt | ||||
loxP | phage P1 loxP | 15 | loxP | ||||
loxP | phage P1 loxP | 15 | loxP |
Phenotype | |
---|---|
Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
---|---|
Donor DNA | Bacteriophage P1 loxP sites, yeast FRT (flippase recombination target) site, mouse Derl1 genomic DNA |
Research application | Cre/loxP system FLP/frt system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. iScience, 24(7):102758 (2021). doi: 10.1016/j.isci.2021.102758. |
Depositor | Hideki Nishitoh (University of Miyazaki) |
Strain Status | ![]() |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
---|
No Data |