Strain Data Sheet

RBRC11832

Strain Information

Image
BRC No.RBRC11832
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129-Crls1<tm1.1Tkato>
Former Common nameCrls(flox/+)
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Cardiolipin is essential for early embryonic viability and mitochondrial integrity of neurons in mammals.
Takaoki Kasahara, Mie Kubota-Sakashita, Yasuko Nagatsuka, Yoshio Hirabayashi, Tomohito Hanasaka, Koujiro Tohyama, Tadafumi Kato
FASEB J., 34(1):1465-1480 (2020). 31914590

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Crls1cardiolipin synthase 12Crls1targeted mutation 1.1, Tadafumi Kato
Frtyeast FRT (flippase recombination target) site2Frt
loxPphage P1 loxP2loxP

Phenotype

Annotation by Mammalian phenotyhpe ontology
Detailed phenotype data

Ordering Information

Donor DNAバクテリオファージP1 loxP配列, 出芽酵母 FRT配列
Research applicationCre/loxP system
FLP/frt system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. FASEB J., 34(1):1465-1480 (2020).Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEVELOPER (Dr. Takaoki Kasahara) using the Approval Form.
DepositorTakaoki Kasahara (RIKEN CBS)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data