Strain Data Sheet
RBRC11856
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC11856 |
| Type | Targeted Mutation Congenic |
| Species | Mus musculus |
| Strain name | B6.Cg-Setdb1<tm1.1Yshk> |
| Former Common name | Eset flox/+ mice, Setdb1 cKO, Eset cKO,Kmt1e cKO |
| H-2 Haplotype | |
| ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
| Background strain | |
| Appearance | |
| Strain development | |
| Strain description | |
| Colony maintenance | |
| References | Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET. Toshiyuki Matsui, Danny Leung, Hiroki Miyashita, Irina A Maksakova, Hitoshi Miyachi, Hiroshi Kimura, Makoto Tachibana, Matthew C Lorincz, Yoichi Shinkai Nature, 464(7290):927-31(2010). 20164836 |
Health Report | |
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| Examination Date / Room / Rack | 2024/12/09Room:3-3Rack:CSentinel mouse program 2024/09/09Room:3-3Rack:CSentinel mouse program |
Gene | |||||||
|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| Frt | yeast FRT (flippase recombination target) site | 3 | Frt | ||||
| Setdb1 MGI:1934229 | SET domain, bifurcated 1 | 3 | Setdb1<tm1.1Yshk> | targeted mutation 1.1, Yoichi Shinkai | |||
| loxP | phage P1 loxP | 3 | loxP | ||||
| loxP | phage P1 loxP | 3 | loxP | ||||
Phenotype | |
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| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
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| Donor DNA | phage P1 loxP sites, yeast FRT (flippase recombination target) site, mouse Setdb1 genomic DNA |
| Research application | Cre/loxP system FLP/frt system |
| Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Nature, 464(7290):927-31 (2010). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. The RECIPIENT must contact the DEPOSITOR in case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
| Depositor | Yoichi Shinkai (RIKEN) |
| Strain Status |  Live mice Frozen sperm |
| Strain Availability | Live mouse (1 to 3 months) |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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| No Data |