Strain Data Sheet
RBRC11886
Strain Information | |
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| Image | |
| BRC No. | RBRC11886 |
| Type | Targeted Mutation Congenic |
| Species | Mus musculus |
| Strain name | B6.Cg-Il15<tm1.1Iku> |
| Former Common name | IL-15-CFP knock-in (KI)、IL-15<CFP> |
| H-2 Haplotype | |
| ES Cell line | KY1.1[(C57BL/6J x 129S6/SvEvTac)F1] |
| Background strain | |
| Appearance | |
| Strain development | |
| Strain description | |
| Colony maintenance | |
| References | Characterization of the IL-15 niche in primary and secondary lymphoid organs in vivo. Guangwei Cui, Takahiro Hara, Szandor Simmons, Keisuke Wagatsuma, Akifumi Abe, Hitoshi Miyachi, Satsuki Kitano, Masaru Ishii, Shizue Tani-ichi, Koichi Ikuta Proc. Natl. Acad. Sci. USA, 111 (5) 1915-20 (2014). 24449915A circulating subset of iNKT cells mediates antitumor and antiviral immunity. Guangwei Cui, Akihiro Shimba, Jianshi Jin, Taisaku Ogawa, Yukiko Muramoto, Hitoshi Miyachi, Shinya Abe, Takuma Asahi, Shizue Tani-Ichi, Johannes M Dijkstra, Yayoi Iwamoto, Kirill Kryukov, Yuanbo Zhu, Daichi Takami, Takahiro Hara, Satsuki Kitano, Yan Xu, Hajime Morita, Moyu Zhang, Lynn Zreka, Keishi Miyata, Takashi Kanaya, Shinya Okumura, Takashi Ito, Etsuro Hatano, Yoshimasa Takahashi, Hiroshi Watarai, Yuichi Oike, Tadashi Imanishi, Hiroshi Ohno, Toshiaki Ohteki, Nagahiro Minato, Masato Kubo, Georg A Holländer, Hideki Ueno, Takeshi Noda, Katsuyuki Shiroguchi, Koichi Ikuta Sci. Immunol., 7(76):eabj8760.(2022). 36269840 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |||||||
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| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| ECFP | Enhanced Cyan Fluorescent Protein (Aequorea victoria) | 8 | ECFP | ||||
| GH | Growth hormone polyA (Bovine) | 8 | GH | ||||
| Il15 MGI:103014 | interleukin 15 | 8 | Il15<tm1.1Iku> MGI:5574316 | targeted mutation 1.1, Koichi Ikuta | |||
| loxP | phage P1 loxP | 8 | loxP | ||||
Phenotype | |
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| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
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| Donor DNA | Aequorea victoria ECFP gene cDNA, Bovine Growth hormone polyA signal, Bacteriophage P1 loxP site, mouse Il15 genomic DNA |
| Research application | Cre/loxP system Fluorescent Proteins/lacZ System |
| Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Sci. Immunol., 7(76):eabj8760.(2022). Proc. Natl .Acad. Sci. USA., 111(5):1915-20 (2014).For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. |
| Depositor | Koichi Ikuta (Kyoto University) |
| Strain Status |  Frozen embryos |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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