Strain Data Sheet

RBRC11917

Strain Information

Image
BRC No.RBRC11917
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129-Atf6<tm1Kamo>
Former Common nameATF6 alpha knockout mice
H-2 Haplotype
ES Cell lineJ1 [129S4/SvJae](D3 subline)
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1.
Keisuke Yamamoto, Takashi Sato, Toshie Matsui, Masanori Sato, Tetsuya Okada, Hiderou Yoshida, Akihiro Harada, Kazutoshi Mori
Dev. Cell, 13, 365-376 (2007). 17765680

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Atf6
MGI:1926157		activating transcription factor 61Atf6<tm1Kamo> targeted mutation 1, Kazutoshi Mori
  • achromatopsia 7(MedGEN)
    • GH Growth hormone polyA (Bovine)1GH
    Ires internal ribosomal entry site (EMCV)1
    lacZ beta-galactosidase (E. coli)1
    loxP phage P1 loxP1loxP
    neo neomycin resistance gene (E. coli)1

    Phenotype

    Annotation by Mammalian phenotyhpe ontology
    Detailed phenotype data

    Ordering Information

    Donor DNAヒト bcl2 遺伝子 exon3 の一部, ウシ 成長ホルモン遺伝子の polyA signal, 大腸菌 lacZ 遺伝子、neomycin 耐性遺伝子, P1 ファージ loxP 配列, 脳心筋炎ウイルス internal ribosomal entry site: IRES
    Research application
    Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Dev. Cell, 13, 365-376 (2007).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is limited to a
    RECIPIENT of a not-for profit institution for a not-for-profit research. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
    DepositorKazutoshi Mori (Kyoto University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data