Strain Data Sheet
RBRC11918
Strain Information | |
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| Image | |
| BRC No. | RBRC11918 |
| Type | Targeted Mutation |
| Species | Mus musculus |
| Strain name | B6.129-Atf6b<tm1Kamo> |
| Former Common name | ATF6 beta knockout mice |
| H-2 Haplotype | |
| ES Cell line | J1 [129S4/SvJae] |
| Background strain | |
| Appearance | |
| Strain development | |
| Strain description | |
| Colony maintenance | |
| References | Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1. Keisuke Yamamoto, Takashi Sato, Toshie Matsui, Masanori Sato, Tetsuya Okada, Hiderou Yoshida, Akihiro Harada, Kazutoshi Mori Dev. Cell, 13, 365-376 (2007). 17765680 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |||||||
|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| Atf6b MGI:105121 | activating transcription factor 6 beta | 17 | Atf6b<tm1Kamo> | targeted mutation 1, Kazutoshi Mori | |||
| GH | Growth hormone polyA (Bovine) | 17 | GH | ||||
| Ires | internal ribosomal entry site (EMCV) | 17 | |||||
| lacZ | beta-galactosidase (E. coli) | 17 | |||||
| loxP | phage P1 loxP | 17 | loxP | ||||
| neo | neomycin resistance gene (E. coli) | 17 | |||||
Phenotype | |
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| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
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| Donor DNA | ヒト bcl2 遺伝子 exon3 の一部, ウシ 成長ホルモン遺伝子の polyA signal, 大腸菌 lacZ 遺伝子、neomycin 耐性遺伝子, P1 ファージ loxP 配列, 脳心筋炎ウイルス internal ribosomal entry site: IRES |
| Research application | |
| Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Dev. Cell, 13, 365-376 (2007).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
| Depositor | Kazutoshi Mori (Kyoto University) |
| Strain Status |  Frozen embryos |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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| No Data |