Strain Data Sheet

RBRC11924

Strain Information

Image
BRC No.RBRC11924
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-Svep1<tm1.1Ksek>
Former Common nameC57BL/6-Svep1<tm1KS>, Svep1-flox, Polydom-flox
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling.
Nanami Morooka, Sugiko Futaki, Ryoko Sato-Nishiuchi, Masafumi Nishino, Yuta Totani, Chisei Shimono, Itsuko Nakano, Hiroyuki Nakajima, Naoki Mochizuki, Kiyotoshi Sekiguchi
Circ. Res., 120(8):1276-1288 (2017). 28179430

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Frt yeast FRT (flippase recombination target) site4Frt
Svep1
MGI:1928849		sushi, von Willebrand factor type A, EGF and pentraxin domain containing 14Svep1<tm1.1Ksek>
MGI:6188639		targeted mutation 1.1, Kiyotoshi Sekiguchi
loxP phage P1 loxP4loxP
loxP phage P1 loxP4loxP

Phenotype

Annotation by Mammalian phenotyhpe ontology
Detailed phenotype data

Ordering Information

Donor DNAphage P1 loxP sites, yeast FRT (flippase recombination target) site, mouse Svep1 genomic DNA
Research applicationCre/loxP system
FLP/frt system
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Circ Res. Apr 14;120(8):1276-1288.(2017)The RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-proit research is requested to enter into a Material Transfer Agreement with Osaka University.
DepositorKiyotoshi Sekiguchi (Osaka University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data