Strain Information | |
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Image | |
BRC No. | RBRC11949 |
Type | Transgene![]() |
Species | Mus musculus |
Strain name | C57BL/6-Tg(Itgae-HBEGF/EGFP)1Ksat |
Former Common name | B6.CD103-LSL-DTR mice、CD103 Tg |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | |
Strain description | |
Colony maintenance | |
References | Gut dysbiosis promotes the breakdown of oral tolerance mediated through dysfunction of mucosal dendritic cells. Tomohiro Fukaya, Tomofumi Uto, Shuya Mitoma, Hideaki Takagi, Yotaro Nishikawa, Moe Tominaga, Narantsog Choijookhuu, Yoshitaka Hishikawa, Katsuaki Sato Cell Rep., 42(5):112431 (2023). 37099426 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
EGFP | Enhanced Green Fluorescent Protein (Aequorea victoria) | UN | EGFP | ||||
Frt | yeast FRT (flippase recombination target) site | UN | Frt | ||||
HBEGF | heparin-binding EGF-like growth factor (human) | UN | HBEGF | ||||
Ires | internal ribosomal entry site (EMCV) | UN | |||||
loxP | phage P1 loxP | UN | loxP | ||||
SV40 polyA | UN |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | P1 bacteriophage loxP sites, Saccharomyces cerevisiae FRT site, E. coli Neomycin resistance gene, EMCV IRES2 sequence, Homo Sapiens HB-EGF cDNA, Aequorea Victoria EGFP cDNA, SV40 STOP sequence, Mus musculus BAC clone RP23-263M10 (Itgae) |
Research application | Cre/loxP system FLP/frt system Fluorescent Proteins/lacZ System |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cell Rep., 42(5):112431 (2023).I acknowledge that RIKEN (and/or its original provider) reserves title to the Material. I will not transfer the Material to any scientists. |
Depositor | Katsuaki Sato (University of Miyazaki) |
Strain Status | ![]() |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- Mouse of the Month Apr 2024 |
BRC mice in Publications |
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No Data |