Strain Data Sheet

RBRC11949

Strain Information

Image
BRC No.RBRC11949
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameC57BL/6-Tg(Itgae-HBEGF/EGFP)1Ksat
Former Common nameB6.CD103-LSL-DTR mice、CD103 Tg
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Gut dysbiosis promotes the breakdown of oral tolerance mediated through dysfunction of mucosal dendritic cells.
Tomohiro Fukaya, Tomofumi Uto, Shuya Mitoma, Hideaki Takagi, Yotaro Nishikawa, Moe Tominaga, Narantsog Choijookhuu, Yoshitaka Hishikawa, Katsuaki Sato
Cell Rep., 42(5):112431 (2023). 37099426

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
EGFP Enhanced Green Fluorescent Protein (Aequorea victoria)UNEGFP
Frt yeast FRT (flippase recombination target) siteUNFrt
HBEGF heparin-binding EGF-like growth factor (human)UNHBEGF
Ires internal ribosomal entry site (EMCV)UN
loxP phage P1 loxPUNloxP
SV40 polyAUN

Phenotype

Annotation by Mammalian phenotyhpe ontology
Detailed phenotype data

Ordering Information

Donor DNAP1 bacteriophage loxP sites, Saccharomyces cerevisiae FRT site, E. coli Neomycin resistance gene, EMCV IRES2 sequence, Homo Sapiens HB-EGF cDNA, Aequorea Victoria EGFP cDNA, SV40 STOP sequence, Mus musculus BAC clone RP23-263M10 (Itgae)
Research applicationCre/loxP system
FLP/frt system
Fluorescent Proteins/lacZ System
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cell Rep., 42(5):112431 (2023).I acknowledge that RIKEN (and/or its original provider) reserves title to the Material. I will not transfer the Material to any scientists.
DepositorKatsuaki Sato (University of Miyazaki)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-
Mouse of the Month Apr 2024

BRC mice in Publications

No Data