Strain Data Sheet
RBRC11950
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC11950 |
| Type | CRISPR/Cas9 |
| Species | Mus musculus |
| Strain name | C57BL/6-Tnfsf15<em1Ksat> |
| Former Common name | B6.Tnfsf15-/- mice、B6.TL1AKO mice |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | |
| Strain description | |
| Colony maintenance | |
| References | Gut dysbiosis promotes the breakdown of oral tolerance mediated through dysfunction of mucosal dendritic cells. Tomohiro Fukaya, Tomofumi Uto, Shuya Mitoma, Hideaki Takagi, Yotaro Nishikawa, Moe Tominaga, Narantsog Choijookhuu, Yoshitaka Hishikawa, Katsuaki Sato Cell Rep., 42(5):112431 (2023). 37099426 |
Health Report | |
|---|---|
| Examination Date / Room / Rack | 2024/11/05Room:2-検Rack:FSentinel mouse program 2024/08/05Room:2-検Rack:FSentinel mouse program |
Gene | |||||||
|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| Tnfsf15 MGI:2180140 | tumor necrosis factor (ligand) superfamily, member 15 | 4 | Tnfsf15<em1Ksat> | endonuclease-mediated mutation 1, Katsuaki Sato | |||
Phenotype | |
|---|---|
| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
|---|---|
| Donor DNA | Mus musculus Mouse a part of Tnfsf15 gene (gRNA-A1), Mus musculus Mouse a part of Tnfsf15 gene (gRNA-A2), Mus musculus Mouse a part of Tnfsf15 gene (gRNA-B1), Mus musculus Mouse a part of Tnfsf15 gene (gRNA-B2), Streptococcus pyogenes Cas9* |
| Research application | Immunology and Inflammation Research |
| Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cell Rep., 42(5):112431 (2023).I acknowledge that RIKEN (and/or its original provider) reserves title to the Material. I will not transfer the Material to any scientists. |
| Depositor | Katsuaki Sato (University of Miyazaki) |
| Strain Status |  Live mice Frozen embryos Frozen sperm |
| Strain Availability | Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) Live mouse (1 to 3 months) |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- Mouse of the Month Apr 2024 |
BRC mice in Publications |
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| No Data |