Strain Data Sheet
RBRC12049
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC12049 |
| Type | Targeted Mutation Congenic |
| Species | Mus musculus |
| Strain name | B6.Cg-Sipa1l1<tm1Taki> |
| Former Common name | SIPA1L1 KO |
| H-2 Haplotype | |
| ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
| Background strain | |
| Appearance | |
| Strain development | |
| Strain description | |
| Colony maintenance | |
| References | SIPA1L1/SPAR1 Interacts with the Neurabin Family of Proteins and is Involved in GPCR Signaling. Ken Matsuura, Shizuka Kobayashi, Kohtarou Konno, Miwako Yamasaki, Takahiro Horiuchi, Takao Senda, Tomoatsu Hayashi, Kiyotoshi Satoh, Fumiko Arima-Yoshida, Kei Iwasaki, Lumi Negishi, Naomi Yasui-Shimizu, Kazuyoshi Kohu, Shigenori Kawahara, Yutaka Kirino, Tsutomu Nakamura, Masahiko Watanabe, Tadashi Yamamoto, Toshiya Manabe, Tetsu Akiyama J. Neurosci., 42(12)2448-2473 (2022). 35121636 |
Health Report | |
|---|---|
| Examination Date / Room / Rack | |
Gene | |||||||
|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| Sipa1l1 MGI:2443679 | signal-induced proliferation-associated 1 like 1 | 12 | Sipa1l1<tm1Taki> | targeted mutation 1, | |||
| lacZ | beta-galactosidase (E. coli) | 12 | |||||
| loxP | phage P1 loxP | 12 | loxP | ||||
| neo | neomycin resistance gene (E. coli) | 12 | |||||
| nls | SV40 large T antigen nuclear localization signal (NLS) | 12 | nls | ||||
Phenotype | |
|---|---|
| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
|---|---|
| Donor DNA | E. coli Neomycin resistant gene, E. coli LacZ gene, Mus musculus Phosphoglycerate kinase promoter (PGK promoter), PI phage loxP sequence, Simian virus 40 large T antigen nuclear localization signal (NLS) |
| Research application | Cre/loxP system Fluorescent Proteins/lacZ System Neurobiology Research |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Neurosci., 42(12)2448-2473 (2022).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The BIOLOGICAL RESOURCE may be used solely for teaching and/or academic research purposes. Any use of the BIOLOGICAL RESOURCE for commercial purposes requires a separate license from the DEPOSITOR prior to distribution. The RECIPIENT shall contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
| Depositor | Tadashi Yamamoto (Okinawa Institute of Science and Technology Graduate University (OIST)) |
| Strain Status |  Frozen sperm |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
|---|
| No Data |