Strain Data Sheet

RBRC12055

Strain Information

Image
BRC No.RBRC12055
TypeTargeted Mutation CongenicCartagena
SpeciesMus musculus
Strain nameC3H.Cg-Rab27b<tm1Tiz>
Former Common nameRab27b KO mice
H-2 Haplotype
ES Cell lineE14 [129P2/OlaHsd]
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Rab27b is expressed in a wide range of exocytic cells and involved in the delivery of secretory granules near the plasma membrane.
Hiroshi Gomi, Kenichi Mori, Shigeyoshi Itohara, Tetsuro Izumi
Mol. Biol. Cell., 18:4377-86 ( 2007). 17761531

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Rab27b
MGI:1931295		RAB27B, member RAS oncogene family18Rab27b<tm1Tiz>
MGI:3834149		targeted mutation 1, Tetsuro Izumi
lacZ beta-galactosidase (E. coli)18
loxP phage P1 loxP18loxP
neo neomycin resistance gene (E. coli)18
nls SV40 large T antigen nuclear localization signal (NLS)18nls

Phenotype

Annotation by Mammalian phenotyhpe ontology
Detailed phenotype data

Ordering Information

Donor DNA大腸菌 LacZ, Neo 耐性遺伝子, マウス PGK, バクテリオファージ loxP 配列, SV40 NLS from large T gene
Research applicationCre/loxP system
Fluorescent Proteins/lacZ System
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Mol. Biol. Cell., 18:4377-86 ( 2007). doi: 10.1091/mbc.e07-05-0409.In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. The RECIPIENT must contact the DEPOSITORs in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorTetsuro Izumi (Gunma University)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data