Strain Data Sheet

RBRC12084

Strain Information

Image
BRC No.RBRC12084
TypeTransgene CongenicCartagena
SpeciesMus musculus
Strain nameD1.Cg-Tg(Col2a1-CIITA)1Skncu
Former Common nameD1CC (DBA/1, Collagen type II promoter/ enhancer-driven CIITA)
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Aberrant MHC class II expression in mouse joints leads to arthritis with extraarticular manifestations similar to rheumatoid arthritis.
Kanazawa S, Ota S, Sekine C, Tada T, Otsuka T, Okamoto T, Sonderstrup G, Peterlin B M
Proc. Natl. Acad. Sci. USA, 103(39):14465-70 (2006). 16980409

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
CIITA class II transactivator (human)UNCIITA rat Col2a1 Promoter, enhancer
HA human influenza virus HA (hemagglutinin) tag sequenceUNHA
neo Klebsella pneumonia Neomycin resistance geneUN
SV40 polyAUN

Phenotype

Annotation by Mammalian phenotyhpe ontology
Detailed phenotype data

Ordering Information

Donor DNAヒト CIITA(cDNA), ウサギ Globin splicing sequence), ラット Type II collagen Promoter, enhancer), ウシシミアンウイルス40 PolyA: D1CC and D1BC locus), インフルエンザウイルス HA: D1CC locus), Klebsella pneumonia Neomycin 耐性遺伝子
Research application
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Proc. Natl. Acad. Sci. U S A., 103(39):14465-70 (2006). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorSatoshi Kanazawa (Nagoya City University)
Strain Statusan icon for Live miceLive mice
an icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovery and QC required prior to distribution
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data