Strain Data Sheet

RBRC12130

Strain Information

Image
BRC No.RBRC12130
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.Cg-Nfil3<tm1.1Kubo>
Former Common nameE4bp4 KO mouse E4bp4-deficient mouse, Nfil3 KO mouse Nfil3-deficient mouse
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells.
Motomura Y, Kitamura H, Hijikata A, Matsunaga Y, Matsumoto K, Inoue H, Atarashi K, Hori S, Watarai H, Zhu J, Taniguchi M, Kubo M
Nat. Immunol., 12(5) 450-459 (2011). 21460847

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Frt yeast FRT (flippase recombination target) site13Frt
Nfil3
MGI:109495		nuclear factor, interleukin 3, regulated13Nfil3<tm1.1Kubo> targeted mutation 1.1, Masato Kubo
loxP phage P1 loxP13loxP

Phenotype

Annotation by Mammalian phenotyhpe ontology
Detailed phenotype data

Ordering Information

Donor DNAEnterobacteria phage P1 loxP, Saccharomvces cerevisiae FRT, DT-A conditional KO FW
Research applicationCre/loxP system
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Nat. Immunol., 12(5) 450-459 (2011).
DepositorMasato Kubo (RIKEN IMS)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data