Strain Data Sheet

RBRC12135

Strain Information

Image
BRC No.RBRC12135
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-F9<tm2.1(hF9_R338L_I316T)Tsuka>
Former Common name
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
F9 coagulation factor IX (human)XF9
F9
MGI:88384		coagulation factor IXXF9<tm2.1(hF9_R338L_I316T)Tsuka> endonuclease-mediated mutation 2.1, Tsukasa Ohmori
  • hemophilia B(DisGeNET, MedGEN)

  • thrombophilia, X-linked, due to factor 9 defect(MedGEN)
    • Frt yeast FRT (flippase recombination target) siteXFrt
    SV40 polyAX

    Phenotype

    Annotation by Mammalian phenotyhpe ontology
    Detailed phenotype data

    Ordering Information

    Donor DNAhuman F9 cDNA (R338L CGA→CTA mutation, I316T ATT→ACT mutation), yeast FRT (flippase recombination target) site, Simian virus 40 SV40 polyA
    Research applicationFLP/frt system
    Mouse Models for Human Disease
    Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.
    DepositorTsukasa Ohmori (Jichi Medical University)
    Strain Statusan icon for Live miceLive mice
    an icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovery and QC required prior to distribution
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data