Strain Data Sheet
RBRC12165
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC12165 |
| Type | Targeted Mutation Congenic |
| Species | Mus musculus |
| Strain name | B6.Cg-Odf2<tm1Ktos> |
| Former Common name | Odf2<tm1Ktos>, Odf2-KO, Odf2+/- |
| H-2 Haplotype | |
| ES Cell line | J1 [129S4/SvJae] |
| Background strain | |
| Appearance | |
| Strain development | |
| Strain description | |
| Colony maintenance | |
| References | Odf2 haploinsufficiency causes a new type of decapitated and decaudated spermatozoa, Odf2-DDS, in mice. Chizuru Ito, Hidenori Akutsu, Ryoji Yao, Keiichi Yoshida, Kenji Yamatoya, Tohru Mutoh, Tsukasa Makino, Kazuhiro Aoyama, Hiroaki Ishikawa, Koshi Kunimoto, Sachiko Tsukita, Tetsuo Noda, Masahide Kikkawa, Kiyotaka Toshimori Sci. Rep., 9(1) 14249 (2019). 31582806 |
Health Report | |
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| Examination Date / Room / Rack | 2024/12/09Room:3-3Rack:DSentinel mouse program 2024/09/09Room:3-3Rack:DSentinel mouse program |
Gene | |||||||
|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| En2 | En2 SA (mouse En2 intron 2/exon 3 splice acceptor sequence) | 2 | En2 | ||||
| GH | bovine GH polyA signal | 2 | GH | ||||
| Ires | internal ribosomal entry site (EMCV) | 2 | |||||
| Odf2 MGI:1098824 | outer dense fiber of sperm tails 2 | 2 | Odf2<tm1Ktos> MGI:6392240 | targeted mutation 1, Kiyotaka Toshimori | |||
| b-geo | lacZ reporter gene and neomycin resistance gene | 2 | b-geo | ||||
| loxP | phage P1 loxP | 2 | loxP | ||||
| loxP | phage P1 loxP | 2 | loxP | ||||
| SV40 polyA signal | 2 | ||||||
Phenotype | |
|---|---|
| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
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| Donor DNA | phage P1 loxP sites, mouse engrailed-2 (En-2), internal ribosomal entry site (EMCV), mouse Phosphoglycerate kinase promoter (PGK promoter), E. coli β-galactosidase/neomycin-resistance fusion gene (β-geo), SV40 polyA signal, bovine GH polyA signal, mouse Odf2 genomic DNA |
| Research application | Cre/loxP system Fluorescent Proteins/lacZ System |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Sci. Rep., 9(1) 14249 (2019). doi: 10.1038/s41598-019-50516-2.For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. |
| Depositor | Chizuru Ito (Chiba University) |
| Strain Status |  Live mice Frozen embryos |
| Strain Availability | Cryopreserved embryos (within 1 month) Live mouse (3 to 6 months) |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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| No Data |