Strain Data Sheet
RBRC12207
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC12207 |
| Type | Transgene |
| Species | Mus musculus |
| Strain name | B6-Tg(Il4-GFP)1Kubo |
| Former Common name | delta 5a/5 Tg, delta Va/V Tg, B-KO |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | |
| Strain description | |
| Colony maintenance | |
| References | The interleukin-4 enhancer CNS-2 is regulated by Notch signals and controls initial expression in NKT cells and memory-type CD4 T cells. Shinya Tanaka, Jun Tsukada, Wataru Suzuki, Katsuhiko Hayashi, Kenji Tanigaki, Masayuki Tsuji, Hiromasa Inoue, Tasuku Honjo, Masato Kubo Immunity, 24(6):689-701 (2006). 16782026The 3' enhancer CNS2 is a critical regulator of interleukin-4-mediated humoral immunity in follicular helper T cells. Yohsuke Harada, Shinya Tanaka, Yasutaka Motomura, Yasuyo Harada, Shin-ichiro Ohno, Shinji Ohno, Yusuke Yanagi, Hiromasa Inoue, Masato Kubo Immunity, 36(2):188-200 (2012). 22365664 |
Health Report | |
|---|---|
| Examination Date / Room / Rack | |
Gene | |||||||
|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| GFP | Green Fluorescent Protein (Aequorea victoria) | ||||||
Phenotype | |
|---|---|
| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
|---|---|
| Donor DNA | Mouse 5’Enhancer, IL-4 promoter, Δ5a 領域（distal3’領域の最初の 1657bp が欠損している）, Aequorea victoria GFP 及びその変異体 |
| Research application | |
| Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Immunity, 24(6):689-701 (2006). |
| Depositor | Masato Kubo (RIKEN IMS) |
| Strain Status |  Frozen embryos |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
|---|
| No Data |