Strain Data Sheet

RBRC12270

Strain Information

Image
BRC No.RBRC12270
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129-Txlna<tm1Hshir>
Former Common nameα-taxilin KO
H-2 Haplotype
ES Cell lineiTL BA1[(C57BL/6N x 129S6/SvEvTac)F1]
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Taxilin; a novel syntaxin-binding protein that is involved in Ca2+-dependent exocytosis in neuroendocrine cells.
Satoru Nogami, Sachie Satoh, Michiko Nakano, Hiroaki Shimizu, Hiromichi Fukushima, Ayumi Maruyama, Akira Terano, Hiromichi Shirataki
Genes to Cells., 8,1:17-28 (2003). 12558796

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Frt yeast FRT (flippase recombination target) site4Frt
Frt yeast FRT (flippase recombination target) site4Frt
Txlna
MGI:105968		taxilin alpha4Txlna<tm1Hshir> targeted mutation 1,
loxP phage P1 loxP4loxP
loxP phage P1 loxP4loxP
neo neomycin resistance gene (E. coli)4 mouse Phosphoglycerate kinase promoter (PGK promoter), synthetic bacterial EM7 promoter (T7 phage)

Phenotype

Annotation by Mammalian phenotyhpe ontology
Detailed phenotype data

Ordering Information

Donor DNAPhage P1 loxP sites, yeast FRT (flippase recombination target) sites, mouse phosphoglycerate kinase promoter (Pgk promoter), EM7 promoter (T7 phage), E. coli neomycin resistant gene, pSP72 vector (Promega, GenBank: X65332)
Research applicationCre/loxP system
FLP/frt system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genes to Cells., 8,1:17-28 (2003).
DepositorShirataki Hiromichi (Dokkyo Medical University)
Strain Statusan icon for Live miceLive mice
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovery and QC required prior to distribution
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data