Strain Data Sheet
RBRC12285
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC12285 |
| Type | CRISPR/Cas9 (Transgene) |
| Species | Mus musculus |
| Strain name | B6-Gt(ROSA)26Sor<em1(CAG-LSL-GREB1_i4)Osb> |
| Former Common name | Greb1 Is4 |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | |
| Strain description | |
| Colony maintenance | |
| References | GREB1 isoform 4 is specifically transcribed by MITF and required for melanoma proliferation. Koei Shinzawa, Shinji Matsumoto, Ryota Sada, Akikazu Harada, Kaori Saitoh, Keiko Kato, Satsuki Ikeda, Akiyoshi Hirayama, Kazunori Yokoi, Atsushi Tanemura, Keisuke Nimura, Masahito Ikawa, Tomoyoshi Soga, Akira Kikuchi Oncogene, 42, 3142-3156 (2023). 37658191 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |||||||
|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| FLAG | FLAG tag (synthetic) | 6 | FLAG | ||||
| GH | Growth hormone polyA (Bovine) | 6 | GH | ||||
| GREB1 Is4 | 6 | GREB1 Is4 | |||||
| Gt(ROSA)26Sor MGI:104735 | gene trap ROSA 26, Philippe Soriano | 6 | Gt(ROSA)26Sor | ||||
| HA | human influenza virus HA (hemagglutinin) tag sequence | 6 | HA | ||||
| loxP | phage P1 loxP | 6 | loxP | ||||
| SV40 polyA signal | 6 | ||||||
Phenotype | |
|---|---|
| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
|---|---|
| Donor DNA | バクテリオファージ loxP, ニワトリ CAG promoter, ヒト GREB1 Is4, ウシ bGH polyA, 合成 DNA FLAG tag, ヒトインフルエンザウイルス HA tag, SV40 ウィルス SV40 poly(A) signal (3 x stop) |
| Research application | Cre/loxP system |
| Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Oncogene, 42, 3142-3156 (2023).The RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University. |
| Depositor | Akira Kikuchi (Osaka University) |
| Strain Status |  Frozen embryos |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering:
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BRC mice in Publications |
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| No Data |