Gene Engineering Division - DNA BANK - > Gene Set Collection

Gene Set Collection

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Diseases

Name Thumbnail Image
Alzheimer disease (GSB0043)  
Amyotrophic lateral sclerosis (ALS) (GSB0044)  
Huntington disease (GSB0045)  
Influenza A relevant genes (GSB0050)  
Parkinson disease (GSB0046)  
SARS-CoV-2 genes and COVID-19 relevant human genes (GSB0049)  

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Pathways

Name Thumbnail Image
Apoptosis (GSB0037)  
Autophagy (GSB0021)

  • The 2016 Nobel Prize in Physiology or Medicine was awarded to Dr. Yoshinori Ohsumi “for his discoveries of mechanisms for autophagy”. Genetic resources for autophagy study are available. Looking forward to receiving your request.
  
Axon guidance (GSB0036)  
B cell receptor signaling pathway (GSB0034)  
Cancer (GSB0055)  
Cell cycle (GSB0054)  
Circadian Clock (GSB0019)
DNA damage (GSB0014)
DNA Repair (GSB0022)

  • Base excision repair
  • Nucleotide excision repair
  • Mismatch repair
  
Endocytosis (GSB0028)  
Ets transcription factor (GSB0005)

  • Ets-1 or PEA-3 activates the MMP (matrix metalloproteinase) promoters in cooperation with AP1 (c-Fos/c-Jun) on the RRE (Ras-response element).
  • TCF (Elk-1, Sap-1, Net) activates the c-fos promoter in cooperation with SRF (serum response factor).
  • PU.1 activates myeloid-specific promoters in cooperation with AML1 and C/EBP.
  • Fli-1 activates megakaryocyte-specific promoters in cooperation with GATA-1.
  • PU.1 activates the immunoglobulin (Ig) heavy (H) chain enhancer in cooperation with E12, Ets-1, TFE3 and Oct-2.
  • Ets-1 activates the T cell receptor (TCR) a enhancer in cooperation with CREB/ATF, TCF-1, AML1 and GATA-3.
Extracellular matrix (ECM) (GSB0053)  
Ferroptosis (GSB0052)  
Hedgehog signaling pathway (GSB0024)  
HIF-1 signaling pathway (GSB0035)  
Hippo signaling pathway (GSB0023)  
Intestinal immune network for IgA production (GSB0039)  
JAK-STAT signaling pathway (GSB0030)  
Lysosome (GSB0029)  
MAPK (GSB0056)  
MAP kinase p38alpha pathway (GSB0003)

  • Mouse, Cell and DNA Resources of p38 MAP (mitogen-activated protein) kinase were originally developed and deposited by Dr. Tatsuhiko SUDO, RIKEN. Those resources are beneficial for the researches focusing on intra- and inter-cellular stress signaling. Also they may be utilized for physiological, pathological and hereditary studies. In addition, the specific DNA clones are designed for p38α inhibitor screening method using growth recovery of bacteria as an index.
Mytophagy (GSB0051)  
NF-kappa B signaling pathway (GSB0031)  
Notch signaling pathway (GSB0025)  
p53, p63 and p73 (GSB0020)  
Regulation of genes in ES cells 01 (GSB0017)
Sphingolipid signaling pathway (GSB0027)

  • Lipid rafts are small lipid domains on the cell membrane and are thought to play an important role in signal transduction, endocytosis and more. Because of the lack of appropriate probes to label sphingomyelin and cholesterol individually, detailed analysis of lipid rafts was difficult.
  • Dr. Toshihide Kobayashi and his colleagues of the former Lipid Biology Laboratory at RIKEN have developed methods to visualize the lipid rafts using probes of lipid binding proteins fused with fluorescent proteins.
  
T cell receptor signaling pathway (GSB0033)  
Toll-like receptor signaling pathway (GSB0038)  
Vesicle Trafic Regulation (GSB0001)  
Wnt signaling pathway (GSB0026)  

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Gene Families

Name Thumbnail Image
CD antigens (GSB0042)  
CRISPR-Cas system (GSB0041)  
Cytochrome P450 (GSB0047)  
Galectin and Lectin (GSB0048)  
Myristoylated Kinase (GSB0032)  
Rab Family (GSB0040)  

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2025.05.06 (T.M. GSB0000e)



 

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